After her post-graduation, she learned the nuances of Cosmetic dermatology from her mentor Dr.Jaishree Sharad for the next 2 years. During this time, she participated in international conferences and acquired global exposure which she incorporated into her practice.

She later started her independent private practice as a dermatologist in Mumbai ( Khar West). During this time, she kept herself academically challenged by organizing and presenting at national-level anti-aging conferences and conducting training workshops for doctors learning cosmetic dermatology.

She is the first author of a chapter in the first-ever Textbook on Cosmetic  Dermatology by Indian authors on Body Contouring. She has also co-authored a chapter on Hair Cosmetics and Hair procedures in another textbook on Aesthetic Dermatology. She has been invited as a speaker and a panelist for several dermatology conferences organized nationally. She also acquired a Fellowship in Cosmetic Laser Surgery from the American Board of Laser Surgery, to further her attempt in providing quality service to her clients.

During this time she also conducted interactive educational workshops on skin and hair care amongst college students, senior citizens, women, corporates, salon owners, and the hospitality industry, to understand their needs and expectations from their skin doctor. For Dr. Vrushali Rane-Khan, every patient; be it a celebrity or commoner, commands the same respect and time.

Apart from being a passionate dermatologist, she’s also a trekker (She completed her Everest base camp trek in 2022) and also takes her daughters for treks.

Dr Vrushali Rane-Khan’s mantra is to make her clients comfortable and confident in their own skin so all the treatments are designed to respect their individuality.